Leica CM1850 Cryostat

  • Professionally Refurbished, Like-New
  • New Compressor
  • 1-Year Warranty
  • Save 40%


Leica CM1850 Cryostat

The Leica CM1850 Cryostat is a powerful cryostat for routine as well as research applications in biology, medicine, and industry. The instrument has been designed for rapid freezing and sectioning of tissue samples.


The operating temperature range (ambient temperature) is 18 to 40 degrees C. The temperature setting range is 0 degrees to -35 degrees C. The Leica CM1850 Cryostat has an actively cooled (-45°C) specimen quick freezing shelf with space for the storage of 10 specimen disks. The Leica CM1850 Cryostat features a Peltier cooling mechanism on the quick freeze shelf to embed your tissue faster. Our refurbished cryostats all come with new compressors, which are the heart of the machine, in addition to a complete rebuild of an all-new refrigeration system – new cap tubes, new refrigerant, new insulation, new peltiers, and new condenser fans. We have an expert refrigeration technician on staff that specializes on cryostat refurbishment.


The Leica 2020-C stainless steel microtome with 2-speed motorized coarse feed moves the specimen towards or away from the blade quickly. The Leica CM1850 Cryostat offers a slow forward speed used in conjunction with a rocking motion of the handwheel to permit the operator to quickly trim away excess OCT and achieve full face of the specimen.

Section thickness settings from 1 to 60um, specimen feed 25mm, vertical stroke 59mm, maximum specimen size 55 x 55mm, specimen orientation 8 degrees, electric coarse feed in slow mode is 0.2mm/s and 0.7mm/s in rapid mode.

The Leica CM1850 Cryostat features a built-in enclosed drain system that reduces the chance of aerosolization of infectious agents. The Leica CM1850 Cryostat has a precision crafted spindle feed and roller bearing slide for precise sectioning qualities and includes an easily removable microtome for quick cleaning to minimize risk of infection. The Leica CM1850 Cryostat is self-diagnosing, with single board microprocessor electronics. It is a virtually maintenance free operation and is ergonomically designed to be used in both standing and sitting positions.

The knife holders CN and CS are equipped with knife guards; on the knife holder CE the glass plate of the anti-roll guide constitutes the knife guard.

It is not necessary to remove the microtome for routine disinfecting of the cryochamber. The instrument is appropriate for spray disinfection with Leica Cryofect.

All specifications related to temperature are valid only up to an ambient temperature of 22 degrees C and an air humidity lower than 60%.




Operator Manual


Blade Holder Assembly
Anti-Roll Plate for Blade Holder
Specimen Disc, 30mm (3)
Tissue Freezing Medium for Frozen Sectioning, 4 oz Bottles in Case of 12
Disposable Blades


H x W x D: 44.8″ x 28.7″ x 28.7″

Weight: 297 lbs

Cooling: -35°C Max (Cryo chamber)

Specimen Head Cooling: No

Quick Freeze Shelf: 10 disc spaces (-45°C max)

Sectioning: 1 to 60 µm: 1 µm increments from 1 to 10 µm 2 µm increments from 10 to 20 µm 5 µm increments from 20 to 60 µm

Additional information




Semi Automatic Cryostats



Dimensions (W x D x H)

29"w x 29"d x 45"h (730x730x1140mm) with handwheel


298 lbs (135 kg)