Leica RM2235 Manual Microtome

  • Professionally Refurbished, Like-New
  • New Blade Holder
  • 1-Year Warranty
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Leica RM2235 Microtome

The Leica RM2235 Microtome is a precision instrument manufactured by Leica Microsystems, a leading provider of laboratory equipment and imaging systems. It is designed for sectioning of biological and industrial samples, and is widely used in histology, pathology, and materials science applications.

The RM2235 Microtome features a precision cutting mechanism that allows for precise and accurate sectioning of samples with a thickness range from 0.5 to 60 micrometers. The cutting angle is adjustable and can be locked in place for consistent results. The instrument also features a large cutting stroke of up to 75mm, which allows for easy and efficient sectioning of large samples.

The microtome’s ergonomic design allows for comfortable operation, even during prolonged use. The instrument’s hand wheel is smooth and easy to rotate, and the section thickness is easily adjustable with the thumb wheel. The microtome’s base is also designed to reduce vibration during operation, providing greater stability and precision.

The RM2235 Microtome is also designed for easy maintenance, with simple and easy-to-use blade holders and easy access to the cutting mechanism. The instrument is also made with durable materials that are resistant to wear and tear, ensuring a long service life.

In summary, the Leica RM2235 Microtome is a high-quality precision instrument designed for sectioning of biological and industrial samples. It features a precision cutting mechanism, adjustable cutting angle, large cutting stroke, ergonomic design, easy maintenance, and durable materials. It is widely used in histology, pathology, and materials science applications and is manufactured by one of the leading providers of laboratory equipment, Leica Microsystems.

Accessories included:


Precision specimen orientation with zero-point reference

Compact, ergonomic overall design

User safety integrated into all aspects of the instrument

Ergonomically located coarse feed wheel for fatigue-free operation

Extremely smooth-running handwheel due to patented force compensation system

Two safety locking mechanisms on the handwheel

Precise knife holder lateral adjustment ensures that the entire width of the blade edge can be used

Single-handed operation specimen clamps

Universal knife holder base for different knife holders

Disposable blade with integrated safety finger protection guard

Spacious magnetized section waste tray

One-piece, easy-to-clean housing


Section thickness:

Setting range: 1 – 60 µm

Setting values:

from 1 -10 µm in 1 µm increments

from 10 – 20 µm in 2 µm increments

from 20 – 60 µm in 5 µm increments

Section thickness indication: viewing window

Coarse Feed: manual via coarse feed wheel

Trim settings: 10, 30 µm

Total horizontal specimen feed: approx. 30 mm

Vertical stroke: 70 mm

Specimen retraction: approx. 60 µm, can be deactivated

Maximum specimen size (W x D x H): 2″w x 2.6″d x 1.2″h (50 x 30 x 66 mm)

Specimen orientation: horizontal: 8°, vertical: 8°

Leica RM2235 Microtome Walkthrough Part 1

Leica RM2235 Microtome Walkthrough Part 2


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Additional information







Dimensions (W x D x H)

16.26"w x 24.33" x 12"h (413x618x305 mm)


75 lbs (34 kg)

Power Requirements