Small Specimens

Some specimens may be very tiny; on the order of less than 0.1 cm. Some methods employ the use of mesh cassettes, “tea bag” biopsy pouches, sponges, wrapping paper, etc. in order to contain the specimen and prevent it from escaping the tissue processing cassette. A disadvantage of the above methods is that upon embedding, the specimen has to be handled yet again, possibly resulting in additional fragmentation of the tissue, or possibly complete tissue loss.

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