Rankin Gives Back to the Community
Rankin Biomedical donated a variety of laboratory supplies to Lake Fenton High School. From syringes to block heaters and stainless steel instruments, the supplies are being put to great use …
#6 IHC Nuts and Bolts
Immunohistochemistry Educational Series In previous installments of the IHC Educational Series, we discussed the specifics of the basic procedures found in the IHC laboratory: immunofluorescence, immunohistochemistry and in situ hybridization. …
#5: In Situ Hybridization
In the previous segments of the IHC Educational Series, immunofluorescence and immunoperoxidase methods were discussed. In both of these methods, antibodies are used to bind to and localize protein antigens …
2019 Michigan Microscopy and Microanalysis Society Meeting
Rankin attended the 2019 Michigan Microscopy and Microanalysis Society (MMMS) Meeting held at Kellogg Hotel and Conference Center in East Lansing, MI on October 31, 2019. Rankin’s tie-in to the …
#4: Antibodies
In the previous units of this series, the immunohistochemical (IHC) methods of immunofluorescence and immunoperoxidase were described and discussed. These methods use antibodies to localize cellular proteins in tissue sections, …
#3: Immunoperoxidase
In the previous segment, immunofluorescence methods were discussed. These methods use antibodies labelled with fluorescein to directly localize cellular proteins in tissue sections, which can then be visualized in a …
#2 Immunofluorescence
Before we discuss immunofluorescence, we need to know what fluorescence is. There are certain substances, composed of molecules that will emit light when irradiated by a short wavelength, such as …
#1 Introduction to Immunohistochemistry
Anthony van Leeuwenhoek is credited with being the first person to use a microscope to view tiny “animacules” in 1674. At approximately the same time, Robert Hooke used a similar …
#7 Tissue Processing Artifacts
The most noticeable tissue processing artifacts are the wrinkles and tears in the tissue sections which are evident even at low power (Figure 1). Incomplete fixation would not cause such …
#6 Understanding Tissue Processor Procedures
Tissue Processing Standard tissue processing may be carried out on any number of open and closed tissue processors, although closed processors are preferred due to safety concerns, both for the …
