Leica ASP300 S Tissue Processor

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Leica ASP300 S Tissue Processor

The Leica ASP300 S Tissue Processor is a top-of-the-line, fully enclosed automated vacuum tissue processor designed for routine and research histopathology. It is capable of processing up to 300 cassette-embedded samples and it features many integrated systems, yet user operations are simplified to reduce operator involvement and the risk of making mistakes. The technician has the freedom to set all critical program parameters to achieve the perfect process and can further control tissue infiltration by modifying the pressure levels inside the retort, as needed.

Minimal reagent carryover – achieved by the software-controlled 3-step draining process of the retort and by the retort design itself – also helps achieve superior specimen quality every time. Proven technology combined with top quality components and Leica´s RemoteCare™ diagnostic (optional) provide superior instrument reliability. The ASP300 S Tissue Processor’s new “RemoteCare” is a built-in software program that helps prevent specimen loss.

Straightforward routine user operations by an intuitive user interface, color touch screen and a variety of “smart” features, such as Reagent Management System (ensures consistent high sample quality with optimized, economic reagent use), and quick start for commonly used programs, improve specimen quality and laboratory economy.

The Leica ASP300 S Tissue Processor features: four cleaning programs, multi-language, 4.5 liter retort with optical level sensor, stir bar, reagent management system, external wax drain and remote fill and drain, 4.3 liter bottles, 15 programs of up to 10 reagents, 10 reagent bottles, 3 cleaning bottles, 1 condensate bottle. Paraffin melt time is 10 hours.

The Lecia ASP300 S Tissue Processor’s software allows immediate access to the various programs and guides the operator safely and smoothly through the system. Frequently used programs can be defined as “Favorites”. A variety of smart features make the ASP300 S one of the most reliable and efficient instruments available for tissue processing. A context-sensitive, online help feature supports the operator in routine tasks and answers the most commonly asked questions about the use of the Leica ASP300 S.

As an option, the Leica ASP300 S Tissue Processor can be equipped with Leica RemoteCare for real-time application and service support via internet connection. Leica RemoteCare remotely monitors the ASP300 S, captures instrument data and proactively resolves potential problems. This helps maximize uptime and the performance of tissue processing.

Technical Specifications:


Maximum capacity – metal basket: 300 cassettes

Maximum capacity – microwaveable plastic basket: 252 cassettes

Retort material: stainless steel

Level sensing: optical sensors

Processing retort volume: 4.3 liters

Paraffin temperature range: 40–65 °C

Reagent temperature range: ambient, 30–55 °C

Temperature accuracy: +/– 1 °C

Retort draining: selectable (80, 120, 140 seconds), 3 steps

Vacuum & pressure options: 4 (V/P, V, P, Ambient)

Vacuum: – 70 kPa (g)

Pressure: +35 kPa (g)

Recirculation (pump in/out)

Time before first cycle: 12 minutes

Time between cycles: 20 minutes

Incubation time: 0–99 hours, 59 minutes

Delayed end-time: programmable, up to one week


Number of paraffin baths 3, connected directly to the retort

Paraffin bath volume 4.3 liters each

Average paraffin melting time: approx. 10 hours


Number of reagent bottles: 10

Reagent bottle volume: 4.3 liters each

Clean cycle bottles: 3, plus 1 external


Display: Color touchscreen, solvent-resistant

Reagent Management System

Remote fill and drain system

Remote paraffin drain system

Two external alarm connections

Baskets, operator manual, tubing and carbon filter included.

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Additional information




Tissue Processors


ASP300 S

Dimensions (W x D x H)

24"w x 27"d x 52"h (59x68x132cm)


309 lbs (140 kg)