Microm HM 325 Manual Microtome


Its standout features include a precision micrometer mechanism with removable setting knobs for user flexibility, zero-backlash vertical specimen movement, and convenient section thickness monitoring. Notably, it excels in specimen retraction during the return stroke, enhancing section quality and tool longevity. With fine specimen orientation and quick-change functionality, it ensures precise alignment with zero-positioning. The microtome’s streamlined knife carrier system minimizes confusion and guarantees safety, while its ergonomic design, including a patented, well-shaped knife carrier insertion and a large, removable section waste tray, optimizes comfort and efficiency during extended use.


Microm HM 325 Microtome: Precision and Versatility Unleashed

Unmatched Versatility

The Microm HM 325 Microtome stands as the quintessential routine and research system, catering to the diverse needs of biological, medical, and industrial laboratories. Its universal appeal lies in its ability to seamlessly transition between paraffin sectioning and manual hard sectioning with unwavering precision.

Precision Micrometer Mechanism

This microtome boasts a precision micrometer mechanism with a unique twist. The removable setting knobs grant the freedom to operate from either the right or left side of the instrument, catering to diverse user preferences. Monitoring section thickness within the range of 0.5 to 60 µm becomes a breeze, thanks to the integrated index window on the front side of the instrument. Zero-backlash vertical specimen movement ensures meticulous precision, even under demanding sectioning conditions.

Effortless Specimen Retraction

One hallmark feature of the HM 325 is its specimen retraction during the return stroke. This ingenious design enhances section quality, streamlines the ribboning of sections, and significantly extends the lifespan of your sectioning tools.

Fine Orientation with Quick Change

When it comes to specimen alignment, the Microm HM 325 sets new standards. Its fine orientation system, coupled with a quick-change function, allows for precise specimen alignment both horizontally (X-axis) and vertically (Y-axis) with zero positioning. Achieving parallel alignment towards the cutting surface is a breeze. Even when using large clamps or a Cool-Cut, ergonomic one-hand operation is facilitated by operating knobs on the left side, ensuring easy accessibility. Rapid replacement of all clamping devices requires the simple loosening of a single lever. Furthermore, the microtome’s flat design minimizes artifacts, especially when dealing with high cutting forces.

Efficient Knife Carrier System

The Microm HM 325 streamlines the sectioning process with its knife carrier system. It presents users with a reduced number of levers, eliminating confusion during operation. Whether you opt for standard knives, tungsten carbide knives, or disposable blades (low and high profile), this microtome accommodates them all for various applications, all equipped with a finger guard for added safety.

Ergonomics at Its Best

Comfort and efficiency go hand in hand with the HM 325. Its patented, well-shaped knife carrier insertion ensures an ergonomic working posture. The entire work area, both behind and below the knife carrier, is covered by a generously sized, removable section waste tray. This tray not only simplifies cleaning but also serves as an armrest for added comfort during extended operation.

Technical Specifications

  • Trimming: Automatic
  • Specimen Movement: Vertical, retraction in the return stroke
  • Section Feed: 0.5 – 60 µm
  • Feed Time for 2µm: 0.5 µm
  • Feed Time for 10µm: 1 µm
  • Feed Time for 20µm: 2 µm
  • Max Horizontal Range: 28 mm
  • Vertical Stroke: 64 mm
  • Capacity: 1100 mL
  • Dimensions: Width 16.53 in, Height 19.29 in, Depth 11 in
  • Weight: 50.7 lbs

The Microm HM 325 Microtome embodies precision, versatility, and ergonomic excellence. It redefines microtomy, ensuring every sectioning task is performed with the utmost precision and comfort, making it the ideal choice for laboratories seeking perfection in their sectioning tasks.

Additional information



HM 325


Dimensions (W x D x H)

16.5" x 19.3" x 11"


50.7 lbs




Operator Manual

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