Thermo Scientific Microm HM 355 S3 Automated Microtome


Explore the pinnacle of microtomy excellence with the Thermo Microm HM355 S3, a microtome that redefines precision in research and analysis. With a cutting stroke of 72mm and a maximum sectioning speed of 400mm/s, it delivers rapid, accurate results. Its intelligent display allows real-time monitoring, while the rocking option enhances trimming efficiency. Compact yet impactful, it includes features like a low or high-profile knife holder, control panel, foot pedal, and waste tray. Elevate your microtomy with the HM355 S3, where precision and innovation unite for exceptional outcomes.


Elevate Precision with the Thermo Microm HM355 S3 Automated Microtome:

Immerse yourself in the world of advanced microtomy with the Thermo Microm HM355 S3 Automated Microtome, an instrument designed to redefine the boundaries of sectioning precision. This microtome builds upon its predecessor’s capabilities while introducing innovative features that cater to the intricate demands of modern research and analysis.

Unparalleled Cutting Dynamics:

The HM355 S3 Automated Microtome stands as a testament to precision, boasting a cutting stroke of 72mm that empowers you to achieve meticulous sectioning results with every pass. With a maximum sectioning speed of 400mm/s, this microtome ensures rapid and efficient processing without compromising on quality. Furthermore, the total specimen advance of 28mm provides unmatched control over the sectioning process.

Versatile Section Thickness and Trim Control:

Seamlessly transition between various applications with the HM355 S3 Automated Microtome’s extensive section thickness range of 0.5-100μm, catering to the diverse needs of your research endeavors. Customize your specimen preparation further with the trim thickness range of 5-500μm, offering flexibility that matches the intricacies of your specimens.

Efficient Trimming Innovation:

Uncover the convenience of the rocking option included in the HM355 S3 Automated Microtome, enabling the specimen head to advance by a set amount for efficient trimming without the need for full handwheel rotations. This innovation streamlines the trimming process and enhances your workflow by saving time and effort.

Intelligent Monitoring and Control:

Experience ultimate control over your microtomy process through the microtome’s integrated display. The display monitors various functions including cutting speed, section count, section thickness, and advance distance, allowing you to stay informed in real-time. This user-friendly feature promotes precision and optimizes your sectioning workflow.

Tailored Flexibility:

The HM355 S3 Automated Microtome adapts to your preferences with the option for a screw-down specimen clamp and a non-disposable steel knife holder. This flexibility ensures that your microtomy setup aligns perfectly with your research requirements.

Precision Meets Innovation:

With the Thermo Microm HM355 S3 Automated Microtome, precision, and innovation converge to offer an unparalleled sectioning experience. Whether you’re engaging in routine histology or advanced research, this microtome empowers you to achieve exceptional results with ease. Trust in its cutting-edge features, intuitive interface, and adaptable options to revolutionize your laboratory’s microtomy capabilities and embark on a journey of enhanced precision and discovery.

Additional information



HM355 S3



Dimensions (W x D x H)

16" x 20.5" x 11"


77 lbs



Operator Manual

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