Leica CM1510 S MOHS Cryostat

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Leica CM1510 S Cryostat

The Leica CM1510 S Cryostat is the best value cryostat available for all cryo- and critical applications such as Mohs surgery.

The Leica CM1510 S Cryostat allows rapid freezing and sectioning of skin in multiple thin layers. Time is crucial when sectioning frozen specimens. An actively cooled quick freezing shelf with defrost function and a powerful refrigeration system are provided to get rapid results.

In a minimum of time, the specimen can be clamped and oriented with the easy-to-use orientation system. Orientation is rapid and produces top quality sections.

The motorized coarse feed enables rapid trimming. Two different speed settings in each direction are provided for improved efficiency.

The actively cooled quick-freezing shelf (-45 °C) with heat extractor allows extremely fast specimen freezing. A manual defrost cycle can be activated whenever necessary.

The perfectly illuminated and insulated cryochamber is easily accessible through a heated sliding window. Ample space is provided for convenient specimen handling.

To ensure protection against injury when changing specimens and/or knives, the Leica CM1510 S Cryostat’s smooth-running handwheel is lockable in the upper position.


Splash-protected high precision microtome

Specimen orientation

Motorized coarse feed in two different speeds

Cryochamber temperature 0 °C to -30 °C

Automated and manual cryochamber defrost cycle

Actively cooled quick freezing shelf, lowest

possible temperature -45 °C, with manual defrost

on demand

Illuminated cryochamber

Heated sliding window, removable

Compact dimensions

Cryocabinet on rollers


Rotary microtome

Section thickness setting: 1 -60 μm

in 1-μm steps from 1 to 10 μm

in 2-μm steps from 10 to 20 μm

in 5-μm steps from 20 to 60 μm

Total horizontal specimen feed: 25 mm

Vertical stroke: 59 mm

Maximum specimen size: 55 x 55 mm

Specimen orientation: 8° (x-, y-, z-axis)

Electrical coarse feed

slow: 0.2 μm/s

fast: 0.7 μm/s

Refrigeration system

Temperature setting range: 0 °C to -30 °C ±10% at ambient temperature of 22°C and air humidity <60% when sliding window is closed

Adjustable in 1-degree increments

Temperature of quick-freezing shelf: Max. -44 °C at a temperature of -30 °C

Defrosting: Automatic hot gas defrosting, defrost time freely programmable, manual defrosting of quick-freeze shelf and evaporator duration: 8 min.

Some of its features and specifications include:

  • Cutting thickness range: 1-10 microns
  • Temperature range of the freezing chamber: -20°C to +20°C
  • Temperature range of the specimen holder: -20°C to +20°C
  • Motorized control of the cutting angle and thickness
  • Automatic freezing of the specimen
  • Automatic defrosting of the specimen
  • Automatic specimen advance
  • Automatic specimen ejection
  • Automatic blade advance
  • Automatic blade ejection
  • Automatic cooling of the specimen
  • Automatic return of the cryochamber to the starting position
  • Compact and ergonomic design for ease of use
  • High-precision sectioning with minimal sample damage
  • Large freezing chamber with a high specimen capacity
  • Motorized control of the cryochamber for ease of use and precise temperature control
  • Automatic safety features to protect the user and the samples
  • Easy to clean and maintain
  • Wide range of accessories and attachments available to suit different applications
  • Automatic cryochamber return to the starting position

Additional information




Semi Automatic Cryostats


CM 1510 S

Dimensions (W x D x H)

27"w x 27"d x 46"h


256 lbs (120kg)